We've once again had a fabulous Mothers Day weekend, spending it with the doctors who helped create Ella. A very special day that Ella looks forward to every year. I'd like to highlight on the founder of GIVF because with out him, Ella would not exist. In fact quite possibly IVF would not be with out him! He is the only surviving team member who created the first ever living IVF baby in England and then created one of the first American IVF programs. I'm attaching his short bio for you to read. He also has a short book titled, "Robert G. Edwards: A personal Viewpoint." I enjoyed reading about it more in depth!
Here is Doctor Schulman with Ella:
Joseph D. Schulman, M.D., founder of the Genetics & IVF
Institute, currently serves as the Chairman of the Institute's Board of
Directors, and was Chief Executive Officer and Medical Director of GIVF
from 1984 until 1998. He is internationally recognized in the fields of
human reproduction and genetics, and is the only American physician to
have trained with Drs. Robert G. Edwards and Patrick Steptoe of Britain,
the inventors of in vitro fertilization (IVF). Dr. Schulman was also
the first director of the Medical Genetics Program at the National
Institutes of Health (NIH), where he was a research scientist and served
on the faculty for ten years. He has served as a consultant to
numerous academic and research institutions, has produced over 200
original contributions to the medical literature, and currently holds an
affiliate professorship at the College of Medicine of Virginia
Commonwealth University, with an additional teaching appointment at the
University of California - San Diego.
Dr. Schulman is well known as one of the pioneers in the creation of
the specialties of assisted reproduction and prenatal genetics in the
United States, and was the impetus behind development of many important
concepts and techniques that have become standard in these important
fields.
After graduating from Harvard Medical School in 1966, Dr. Schulman
originally trained in pediatrics at the Massachusetts General Hospital
(1966-68) and then did a genetics fellowship at the NIH (1968-70).
While at NIH, he decided to specialize in the fields of human genetics
and reproduction, and subsequently was fully trained in obstetrics and
gynecology at the New York Hospital-Cornell Medical Center. He felt that
the combination of all these disciplines would provide a unique
foundation of formal qualifications for pursuing his medical and
research interests.
Before commencing a research career at the National Institute of
Child Health and Human Development (NICHD) at the NIH, Dr. Schulman
became aware of the revolutionary research of Drs. Robert G. Edwards and
Patrick Steptoe, who were working in England to develop the original
methods for IVF. With the support of fellowships from the March of
Dimes (obtained with the help of its eminent President, Dr. Virginia
Apgar) and Harvard Medical School (Gilbert Fellowship) from 1973 through
1974, he worked directly with Drs. Edwards and Steptoe in Cambridge and
Manchester, England. While there, he helped develop some of the first
methods for obtaining and successfully fertilizing human eggs and
cultivating human embryos in vitro (outside the body).
Returning from England in 1974, Dr. Schulman became the head of the
Section on Human Biochemical Genetics at NICHD where he remained until
1983. During his tenure at the NIH he conducted extensive research and
published numerous scientific papers on human genetic diseases, and also
founded and directed the NIH Interinstitute Program in Medical
Genetics.
After the birth of the first IVF babies in England, Dr. Schulman left
NIH and started one of the first American IVF programs while becoming a
Professor at George Washington University. While at GW he hired Andrew
Dorfmann as senior IVF embryologist. Their collaboration has endured
over two decades since their subsequent creation of GIVF, and Andy
continues as the Institute's head of embryology. GIVF was formed as a
joint venture with the Fairfax Hospital Association, now known as Inova
Health System, one of the largest regional hospital systems in the
United States.
GIVF was founded on several core insights that created the model for
IVF centers across the country and around the world. An important
component of this model was to provide IVF treatment on an outpatient
basis using non-surgical ultrasound guided egg retrieval. GIVF was the
very first in the United States to do IVF with this technique instead of
laparoscopy. Dr. Schulman heralded this innovation in an article in the New England Journal of Medicine.
For the first time, IVF patients did not require general anesthesia or
hospitalization to obtain eggs. This made infertility treatment more
available to and far less intrusive for patients. GIVF also conceived
providing infertility treatment in combination with genetic services, an
integration which improves quality of care and efficiency and sets GIVF
apart from virtually all other infertility facilities.
In the area of genetic screening GIVF was also a trailblazer. GIVF
was one of the world's first centers to introduce prenatal genetic
testing via CVS (chorionic villus sampling) as an early, first trimester
alternative to amniocentesis. Today GIVF has what it believes to be
the largest aggregate institutional experience with CVS in the United
States. In addition, GIVF was among the first to utilize real-time
ultrasound guidance of the amniocentesis needle for safer performance of
that procedure with lower risk of fetal injury. Of at least equal
importance, GIVF introduced new laboratory techniques for the culture of
amniocytes (amniotic fluid cells) which reduced the waiting time for
results from 6 weeks to about 8-10 days. This enormously decreased
patient anxiety and proved immensely popular with patients and referring
physicians.
In the mid 1980s GIVF started the Fairfax Cryobank in order to create
an alternative to the then prevailing method of donor insemination with
fresh sperm (a method which GIVF never employed). Instead, Fairfax
Cryobank made available frozen sperm released from quarantine for sale
only after an extended time period followed by retesting of the donors
to ensure the avoidance of genetic and infectious diseases. In the mid
1980s GIVF also introduced one of America's first Donor Egg IVF
programs which, over the ensuing decades, has become one of the
recognized leaders in the field. Today Fairfax Cryobank is one of the
two largest cryobanks in the United States, and GIVF is the only
infertility facility to offer both its own major donor sperm and donor
egg programs.
In the next decade, under Dr. Schulman's leadership GIVF started one
of the first preimplantation genetic diagnosis (PGD) laboratories in the
United States. This facility made it possible for GIVF to test IVF
embryos for genetic factors and to prevent genetic diseases in the
offspring of at-risk families. The Institute's PGD program is now one
of the national leaders in both quality and volume, and has developed
several important new disease-related PGD tests. Dr. Schulman also
conceived and implemented the innovation of using non-disclosing PGD for
the prenatal prevention of Huntington disease, and the Institute has
now helped more Huntington families have disease-free children than any
facility in the world.
In the mid 1990s Dr. Schulman, being continuously attentive to the
latest scientific research, learned of a team in Belgium that had
developed a new technique called ICSI, (intracytoplasmic sperm
injection) for successfully microinjecting a single human sperm into a
living egg. This promised to be revolutionary for the treatment of male
infertility in the frequent cases where, even when using IVF, the sperm
were unable to spontaneously penetrate into the egg. GIVF was the
first infertility clinic in the United States to use ICSI and was the
first in America to report pregnancies using that method. Dr. Schulman
described this pioneering ICSI experience in a major address at the 1994
meeting of the American Fertility Society.
In the mid 1990s, the Institute, under Dr. Schulman's leadership,
developed an entirely new method called NSA (non-surgical sperm
aspiration) for non-surgical treatment of certain cases of male
infertility. NSA avoided the need for testicular surgery and also for
vasectomy reversals, and could be effectively combined with ICSI. This
new method was highly successful and popular with patients, and was
copied all over the world.
Around the same time, under Dr. Schulman’s direction, GIVF started
the first human program in the world for preserving female reproduction
prior to cancer treatment using cryopreservation of ovarian tissue
slices.
Also in the 1990s, Dr. Schulman recognized that a breakthrough
technique being utilized in animals for gender selection had the
potential to be adopted for use in humans. He understood that new
methods of DNA testing (fluorescence in situ hybridization, FISH)
already in use by the Institute’s genetics labs were the key to safely
and rapidly examining the feasibility of sorting human sperm.
Preliminary testing of this concept was successful, and today GIVF holds
the worldwide exclusive license for sperm sorting in humans. Dr.
Schulman named this highly innovative approach MicroSort® and began a
clinical trial with the FDA that is ongoing at the present time and has
already resulted in the births of hundreds of normal children.
Before retiring from full-time active medical duty with the
Institute, Dr. Schulman recognized yet another significant avenue for
marrying the Institute's broad medical and scientific capabilities with a
market opportunity. In the late 1990s GIVF established the first two
modern IVF centers in China, first in Shanghai and then subsequently in
Guangzhou. GIVF, which has always attracted international patients in
search of treatment, was now able to take its capabilities beyond the
United States.
Today Dr. Schulman is an active member of the GIVF Board of
Directors, serving as its Chairman. He pursues his lifelong thirst for
new ideas and developments in reproduction and genetics by continuing to
study the latest scientific and professional developments and helping
to catalyze continuing GIVF innovations. As an obstetrician,
pediatrician, geneticist, luminary in the field of human reproduction,
and former research scientist, Dr. Schulman embodies what GIVF has come
to represent.
Dr. Schulman published Robert G. Edwards: A Personal Viewpoint
in 2010, a personal account of Dr. Schulman's work with Nobel Laureate
Robert Edwards on the development of the original methods of IVF. To request a free copy, click here. To read Dr. Schulman's personal appreciation of Nobel Laureate Robert G. Edwards, click here.
Today GIVF is the leader for combining infertility treatment and
genetics for the delivery of important, pioneering, high quality medical
treatment, and patient care. GIVF continues to be an organization not
only where outstanding medical care is offered, but also one firmly
dedicated to expanding its well-deserved reputation as a center where
scientific knowledge and innovation are created and highly valued, and
where the latest reproductive and genetic innovations are transformed
from theory into everyday practice.
Here are more photos from the event, it's always so much fun! From Clowns making balloons, face painting, that unique and special animal given out each year (our collection is growing), to the buffet of endless food, and most importantly spending it with these lovely men who sincerely love these little humans that they've created!
Wednesday, May 13, 2015
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